Sileo
Oromucosal gel for noise-phobia events such as fireworks, thunderstorms or gunshots. Applied to the gum 30-60 minutes before the trigger. Active ingredient: dexmedetomidine.
See your saving over a year
Pick your dog's weight (and optionally your vet's actual quote) to see the exact monthly and annual saving. The price comparison table below sorts pharmacies by cheapest first; we never sort by commission.
Based on a 15 kg dog, recommended strength: 0.1 mg/ml. Assumes 12 months of continuous use (chronic dosing) and one written prescription per year. CMA Order caps the prescription fee at £21 for the first medicine, plus £12.50 per additional medicine on the same prescription. Prices are indicative and last verified 2026-05-15. Always confirm the current price on the pharmacy site before purchase.
Why it costs more at the vet
Highly seasonal stock; vets stockpile pre-firework season and price accordingly. Online stays priced consistently across the year.
Common side effects
- Mild sedation
- Vomiting (rare)
Not a complete list. Always read the patient information leaflet and speak to your vet about side effects.
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Copy-paste email template, prescription steps and refill setup. From "I just paid too much at the vet" to "I'm saving £X every month".
How to get a written prescription
The CMA Order is legally binding by 23 September 2026. Every UK vet must offer a written prescription on request, with the fee capped at £21 for the first medicine plus £12.5 per additional medicine on the same prescription. Take the prescription to any VMD-approved online pharmacy listed above.
Common questions
- How quickly does Sileo work?
- Most dogs settle within 30-60 minutes. Effects last 2-3 hours; the dose can be repeated up to 5 times in an event night.
- Can I use Sileo every weekend during firework season?
- It is intended for situational use. Speak to your vet about a behaviour plan if anxiety is becoming frequent.
Similar medications
Track Sileo price drops
We'll email when Sileo drops in price at any of the pharmacies above.
Stop overpaying for Sileo.
Same medicine, same regulator, same vet relationship — half the price. Five-minute switch from in-clinic dispensing to a VMD-approved online pharmacy.
Pricing data status: indicative. Last verified 2026-05-15. Pharmacies change prices regularly — always confirm before purchase. Not medical advice.